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Cyberonics Announces First Implant Of AspireSR™ Seizure Response Product In European Trial

Cyberonics, Inc. (Nasdaq: CYBX), a global leader in epilepsy management, announced the first implant of its AspireSR™ seizure response product on April 27, 2011.

The implant, conducted under the care of Professors Paul Boon and Dirk Van Roost and their teams at the Ghent University Epilepsy Group in Ghent, Belgium, was received by a patient with ictal tachycardia (heart rate increases associated with seizures) who has been suffering with epilepsy for many years.

The company's approved products allow the patient to induce additional stimulation manually through the use of a magnet, but do not currently sense the onset of seizures. The AspireSR product automates the magnet stimulation by sensing heart rate changes that are correlated with the patient's seizure activity. The generator then provides stimulation of the vagus nerve in response to the seizure.

"This is an important milestone in the development of treatments for epilepsy, a particularly challenging condition affecting almost three million people in the U.S., and corresponding numbers worldwide," said Dan Moore, Cyberonics' President and Chief Executive Officer. "It also represents significant progress in our development of improvements to the VNS Therapy® System. We look forward to completing the enrollment of this clinical trial, E-36."

"We are pleased to be able to initiate the first implant of this new product," said Professor Boon. "The design is consistent with existing VNS devices, and the procedure was conducted in the usual manner, but the ability of the device to sense changes correlated with a seizure and induce responsive stimulation of the vagus nerve is unique. The new device will be particularly significant for patients who are unable to use a magnet for additional stimulation."

About Cyberonics, Inc. and the VNS Therapy® System

Cyberonics, Inc. is a medical technology company with core expertise in neuromodulation. The company developed and markets the VNS Therapy System, which is FDA-approved for the treatment of refractory epilepsy and treatment-resistant depression. The VNS Therapy System uses a surgically implanted medical device that delivers electrical pulsed signals to the vagus nerve. Cyberonics markets the VNS Therapy System in selected markets worldwide.

Source: Cyberonics, Inc



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